Application Note
Induces pluripotent stem cell (iPS) formation and improves reprogramming efficiency of human and mouse somatic cells by inhibiting apoptosis mediated by the receptors DCC or UNC5B (at 150ng /ml). Induces axon outgrowth.
Product Note
Binds to human, mouse and rat UNC5B.
Form
Lyophilized powder
Buffer
Reconstitute with 100μl ddH₂O to 0.1mg/ml. Lyophilized from 0.2μm-filtered PBS.
Preservative
No preservative
Storage
Store at -20ºC or below. After reconstitution, keep as concentrated solution. Aliquot and avoid freeze-thaw cycles.
Region/Sequence
Human netrin-1 (a.a. 25-604) is fused at the C-terminus to the Fc portion of human IgG1.
Expression System
HEK293 cells
Purity
??95% by SDS-PAGE.
Endotoxin
< 0.1 EU/μg
Conjugation
Unconjugated
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.