APPLICATION
Calculated MW
Observed MW
19 kDa.
PROPERTIES
Form
Lyophilized powder
Buffer
Batch dependent (please contact us for details)
Storage
Store at -20ºC or below. After reconstitution, keep as concentrated solution. Avoid freeze-thaw cycles.
Region/Sequence
C-terminal poly His tagged; Met1-Cys144 of Human PLA2G2A protein (NP_000291.1)
Expression System
HEK293 cells
Purity
> 97% by SDS-PAGE.
Endotoxin
< 1.0 EU/μg (determined by LAL method)
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
phospholipase A2 group IIA , MOM1 , PLA2 , PLA2B , PLA2L , PLA2S , PLAS1 , sPLA2
Cellular Localization
Cell membrane , Secreted
Background
The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.[provided by RefSeq, Sep 2009]
Database
Research Area
DATA IMAGES
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GTX01242-pro Image
SDS-PAGE of 5 μg GTX01242-pro Human PLA2G2A protein, His tag.
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REFERENCE
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REVIEW
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