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Human Parathyroid Hormone protein (active)

Human Parathyroid Hormone protein (active). GTX67104-pro

Cat. No. GTX67104-pro

Application

 Functional Assay

Species

 Human
Package
10 μg ($199)
See all Parathyroid Hormone protein products

APPLICATION

Application Note

Measured by its ability to induce cAMP accumulation in MC3T3/E1 mouse preosteoblast cells. The ED₅₀ for this effect is less than or equal to 50 ng/ml.

PROPERTIES

Form

Liquid

Buffer

PBS (pH7.4), 2mM EDTA

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Region/Sequence

Length: 85 a.a. Sequence: MSVSEIQLMH NLGKHLNSME RVEWLRKKLQ DVHNFVALGA PLAPRDAGSQ RPRKKEDNVL VESHEKSLGE ADKADVNVLT KAKSQ

Expression System

E. coli

Purity

> 95% by SDS-PAGE.

Endotoxin

< 1.0 EU/μg (determined by LAL method)

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

parathyroid hormone , PTH1

Background

This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. On the other hand, defective processing of the encoded protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Database

Research Area

DATA IMAGES

Human Parathyroid Hormone protein (active). GTX67104-pro

GTX67104-pro Image

3 μg of GTX67104-pro Human Parathyroid Hormone protein (active) by SDS-PAGE under reducing condition and visualized by coomassie blue stain

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SDS
PBS.pdf
Package List Price ($)
$ 199