Form
Liquid
Buffer
20mM Tris-HCl, 0.4M Urea, 10% Glycerol
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Region/Sequence
Full length protein, N-terminal His-Tag; MGSSHHHHHH SSGLVPRGSH MGSMSSGYSS LEEDAEDFFF TARTSFFRRA PQGKPRSGQQ DVEKEKETHS YLSKEEIKEK VHKYNLAVTD KLKMTLNSNG IYTGFIKVQM ELCKPPQTSP NSGKLSPSSN GCMNTLHISS TNTVGEVIEA LLKKFLVTES PAKFALYKRC HREDQVYACK LSDREHPLYL RLVAGPRTDT LSFVLREHEI GEWEAFSLPE LQNFLRILDK EEDEQLQNLK RRYTAYRQKL EEALREVWKP D
Expression System
E. coli
Purity
> 85% by SDS-PAGE.
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
Ras association domain family member 3 , RASSF5
Cellular Localization
Cytoplasm,Cytoplasm, cytoskeleton
Background
The RAS oncogene (MIM 190020) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily are plasma membrane GTP-binding proteins that modulate intracellular signal transduction pathways. A subfamily of RAS effectors, including RASSF3, share a RAS association (RA) domain.[supplied by OMIM, Jul 2003]
Database
Research Area