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Human RGS1 protein, His tag

Human RGS1 protein, His tag. GTX67746-pro

Cat. No. GTX67746-pro

Species

Human
Package
100 μg ($389)

APPLICATION

Observed MW

24 kDa.

PROPERTIES

Form

Liquid

Buffer

20mM Tris-HCl, 0.15M NaCl, 10% Glycerol, 1mM DTT

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.25 mg/ml (Please refer to the vial label for the specific concentration.)

Region/Sequence

Full length protein, N-terminal His-Tag; MGSSHHHHHH SSGLVPRGSH MGSHMRAAAI STPKLDKMPG MFFSANPKEL KGTTHSLLDD KMQKRRPKTF GMDMKAYLRS MIPHLESGMK SSKSKDVLSA AEVMQWSQSL EKLLANQTGQ NVFGSFLKSE FSEENIEFWL ACEDYKKTES DLLPCKAEEI YKAFVHSDAA KQINIDFRTR ESTAKKIKAP TPTCFDEAQK VIYTLMEKDS YPRFLKSDIY LNLLNDLQAN SLK

Expression System

E. coli

Purity

> 90% by SDS-PAGE.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

regulator of G protein signaling 1 , 1R20 , BL34 , HEL-S-87 , IER1 , IR20

Cellular Localization

Cell membrane,Cytoplasm, cytosol

Background

This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Human RGS1 protein, His tag. GTX67746-pro

GTX67746-pro Image

3μg Human RGS1 protein (GTX67746-pro) by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Package List Price ($)
$ 389