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Human RPL5 protein, His tag

Human RPL5 protein, His tag. GTX67756-pro

Cat No. GTX67756-pro

Species

Human
Package
50 μg ($359)

APPLICATION

Observed MW

34 kDa.

PROPERTIES

Form

Liquid

Buffer

20 mM Tris-HCl buffer (pH 8.0) with 0.15 M NaCl, 10% glycerol, 1 mM DTT.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.25 mg/ml (Please refer to the vial label for the specific concentration.)

Region/Sequence

Full length protein, N-terminal His-Tag; MGSSHHHHHH SSGLVPRGSH MGSMGFVKVV KNKAYFKRYQ VKFRRRREGK TDYYARKRLV IQDKNKYNTP KYRMIVRVTN RDIICQIAYA RIEGDMIVCA AYAHELPKYG VKVGLTNYAA AYCTGLLLAR RLLNRFGMDK IYEGQVEVTG DEYNVESIDG QPGAFTCYLD AGLARTTTGN KVFGALKGAV DGGLSIPHST KRFPGYDSES KEFNAEVHRK HIMGQNVADY MRYLMEEDED AYKKQFSQYI KNSVTPDMME EMYKKAHAAI RENPVYEKKP KKEVKKKRWN RPKMSLAQKK DRVAQKKASF LRAQERAAES

Expression System

E.coli

Purity

> 85% by SDS-PAGE.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

ribosomal protein L5 , L5 , MSTP030 , PPP1R135 , uL18

Cellular Localization

Cytoplasm,Nucleolus

Background

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18P family of ribosomal proteins and component of the 60S subunit. The encoded protein binds 5S rRNA to form a stable complex called the 5S ribonucleoprotein particle (RNP), which is necessary for the transport of nonribosome-associated cytoplasmic 5S rRNA to the nucleolus for assembly into ribosomes. The encoded protein may also function to inhibit tumorigenesis through the activation of downstream tumor suppressors and the downregulation of oncoprotein expression. Mutations in this gene have been identified in patients with Diamond-Blackfan Anemia (DBA). This gene is co-transcribed with the small nucleolar RNA gene U21, which is located in its fifth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. [provided by RefSeq, Mar 2017]

Database

Research Area

DATA IMAGES

Human RPL5 protein, His tag. GTX67756-pro

GTX67756-pro Image

3μg Human RPL5 protein (GTX67756-pro) by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Package List Price ($)
$ 359