APPLICATION
Application Note
Measured by its ability to transfer sulfate from PAPS to 1-Napthol. The specific activity is > 150 pmoles/min/μg.
Observed MW
34 kDa.
PROPERTIES
Form
Lyophilized powder
Buffer
Batch dependent (please contact us for details)
Storage
Store at -20ºC or below. After reconstitution, keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
Region/Sequence
N-terminal polyhistidine tag; Glu2-Leu295 (NP_808220.1)
Expression System
E. coli
Purity
> 94 % by SDS-PAGE.
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
sulfotransferase family 1A member 3 , HAST , HAST3 , M-PST , ST1A3 , ST1A3/ST1A4 , ST1A4 , ST1A5 , STM , TL-PST
Cellular Localization
Cytoplasm
Background
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a phenol sulfotransferase with thermolabile enzyme activity. Four sulfotransferase genes are located on the p arm of chromosome 16; this gene and SULT1A4 arose from a segmental duplication. This gene is the most centromeric of the four sulfotransferase genes. Read-through transcription exists between this gene and the upstream SLX1A (SLX1 structure-specific endonuclease subunit homolog A) gene that encodes a protein containing GIY-YIG domains. [provided by RefSeq, Nov 2010]
Database
DATA IMAGES
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GTX03579-pro Image
SDS-PAGE of GTX03579-pro Human SULT1A3 (mature) protein, His tag (active).
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REFERENCE
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REVIEW
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