GeneTex

  • Country / Location Selection

United States (US)

Human TCL1A protein

Human TCL1A protein. GTX67964-pro

Cat. No. GTX67964-pro

Species

 Human
Package
100 μg ($259)
See all TCL1A protein products

APPLICATION

Observed MW

13 kDa.

PROPERTIES

Form

Liquid

Buffer

50mM Tris-HCl buffer (pH7.5), 10% Glycerol

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Region/Sequence

Full length protein, MAECPTLGEA VTDHPDRLWA WEKFVYLDEK QHAWLPLTIE IKDRLQLRVL LRREDVVLGR PMTPTQIGPS LLPIMWQLYP DGRYRSSDSS FWRLVYHIKI DGVEDMLLEL LPDD

Expression System

E. coli

Purity

> 90% by SDS-PAGE.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

T cell leukemia/lymphoma 1A , TCL1

Cellular Localization

Cytoplasm,Nucleus,Microsome,Endoplasmic reticulum

Background

Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).[supplied by OMIM, Jul 2010]

Database

Research Area

DATA IMAGES

Human TCL1A protein. GTX67964-pro

GTX67964-pro Image

3μg Human TCL1A protein (GTX67964-pro) by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

REFERENCE

There are currently no references for Human TCL1A protein (GTX67964-pro). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for Human TCL1A protein (GTX67964-pro). Be the first to share your experience with this product.
Submit a Review
SDS
Glycerol.pdf
Package List Price ($)
$ 259