GeneTex
  • Country / Location Selection

United States (US)

Human TGF Alpha protein (active)

Cat No. GTX48352-pro

Application

Functional Assay

Species

Human
Package
100 μg ($369)
PRODUCT

Summary

Recombinant human TGF-α is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.

APPLICATION

Application Note

The ED₅₀ was determined by the dose-dependent stimulation of thymidine uptake by BALB/c 3T3 cells is < 0.2 ng/ml, corresponding to a specific activity of > 5 x 10⁶ units/mg.

PROPERTIES

Form

Lyophilized powder

Buffer

Batch dependent (please contact us for details)

Storage

Store at -20ºC or below. After reconstitution, keep as concentrated solution. Avoid freeze-thaw cycles.

Region/Sequence

VVSHFNDCPD SHTQFCFHGT CRFLVQEDKP ACVCHSGYVG ARCEHADLLA

Expression System

E. Coli

Purity

> 98%

Endotoxin

< 1 EU/μg

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

transforming growth factor alpha , TFGA

Background

This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Database

  • Gene ID: 7039 TGFA

Research Area

REFERENCE

There are currently no references for Human TGF Alpha protein (active) (GTX48352-pro). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Human TGF Alpha protein (active) (GTX48352-pro). Be the first to share your experience with this product.