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Human TRAIL protein, His tag (active)

Cat. No. GTX65668-pro

Application

 Functional Assay

Species

 Human
Package
20 μg ($459)
See all TRAIL protein products

APPLICATION

Application Note

Induces apoptosis at concentrations of > 1 ng/ml. Note: Does not require a cross-linking enhancer for its potentBiological activity. Shows superior activity on human cell lines that require extensive cross-linking of TRAIL-Rs for killing (e.g. Jurkat).

Product Note

Binds to human TRAIL receptors.

PROPERTIES

Form

Liquid

Buffer

20mM HEPES (pH7.4), 150mM NaCl, 0.005% Tween-20, 1% Sucrose, 1mM DTT

Preservative

No preservative

Storage

Store as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Region/Sequence

N-terminal His-Tag; a.a. 95-281. The active multimeric conformation is stabilized by an inserted mutation allowing an additional CC-bridge.

Expression System

E. coli

Purity

??98% by SDS-PAGE.

Endotoxin

< 0.01 EU/μg

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

TNF superfamily member 10 , APO2L , Apo-2L , CD253 , TL2 , TNLG6A , TRAIL

Database

  • Gene ID: 8743 TNFSF10

Research Area

REFERENCE

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REVIEW

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Package List Price ($)
$ 459