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Human UBE2D2 protein, His tag

Human UBE2D2 protein, His tag. GTX67916-pro

Cat. No. GTX67916-pro

Species

 Human
Package
100 μg ($289)
See all UBE2D2 protein products

APPLICATION

Observed MW

17 kDa.

PROPERTIES

Form

Liquid

Buffer

20mM Tris-HCl buffer (pH8.0), 10% Glycerol, 1mM DTT, 0.1M NaCl

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Region/Sequence

Full length protein, N-terminal His-Tag; MGSSHHHHHH SSGLVPRGSH MALKRIHKEL NDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF FLTIHFPTDY PFKPPKVAFT TRIYHPNINS NGSICLDILR SQWSPALTIS KVLLSICSLL CDPNPDDPLV PEIARIYKTD REKYNRIARE WTQKYAM

Expression System

E. coli

Purity

> 95% by SDS-PAGE.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ubiquitin conjugating enzyme E2 D2 , E2(17)KB2 , PUBC1 , UBC4 , UBC4/5 , UBCH4 , UBCH5B

Background

Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]

Database

Research Area

DATA IMAGES

Human UBE2D2 protein, His tag. GTX67916-pro

GTX67916-pro Image

3μg Human UBE2D2 protein (GTX67916-pro) by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

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SDS
Glycerol.pdf
Package List Price ($)
$ 289