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Human VEGFC protein, His tag (active)

Human VEGFC protein, His tag (active). GTX01374-pro
Human VEGFC protein, His tag (active). GTX01374-pro

Cat No. GTX01374-pro

Application

Functional Assay

Species

Human
Package
100 μg ($329),
50 μg ($249)

APPLICATION

Application Note

1. Measured by its binding ability in a functional ELISA. Scatchard analysis showed the affinity constant (Kd) of recombinant human VEGF-C bound to recombinant human VEGFR3 protein was 1.4 nM.
2. Measured in a cell proliferation assay using HUVEC cells. The ED₅₀ for this effect is 0.1-0.5 μg/ml.

Observed MW

22-24 kDa.

PROPERTIES

Form

Lyophilized powder

Buffer

Batch dependent (please contact us for details)

Storage

Store at -20ºC or below. After reconstitution, keep as concentrated solution. Avoid freeze-thaw cycles.

Region/Sequence

C-terminal poly His tagged; Thr103-Arg227 of Human VEGFC protein (NP_005420.1)

Expression System

HEK293 cells

Purity

> 95% by SDS-PAGE.

Endotoxin

< 1.0 EU/μg (determined by LAL method)

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Flt4-L,LMPH1D,VRP

Background

The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. The encoded protein promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. The proprotein is further cleaved into a fully processed form that can bind and activate VEGFR-2 and VEGFR-3 receptors. [provided by RefSeq, Apr 2014]

Database

Research Area

DATA IMAGES

Human VEGFC protein, His tag (active). GTX01374-pro

GTX01374-pro Image

SDS-PAGE of 5 μg GTX01374-pro Human VEGFC protein, His tag (active).

Human VEGFC protein, His tag (active). GTX01374-pro

GTX01374-pro Functional Assay Image

The protein activity of GTX01374-pro Human VEGFC protein was measured in a cell proliferation assay using HUVEC cells.
ED₅₀ : 0.1-0.5 μg/ml

REFERENCE

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Package List Price ($)
$ 329
$ 249