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United States (US)

Human VEGFC protein (active)

Cat No. GTX48342-pro

Application

Functional Assay

Species

Human
Package
20 μg ($319)
PRODUCT

Summary

Recombinant Human VEGF-C is a disulfide-linked homodimeric protein consisting of two 13.5 kDa polypeptide chains of 116 amino acid residues. Due to glycosylation, the protein migrates as a 30.0-33.0 kDa band by SDS-PAGE analysis under non-reducing conditions.

APPLICATION

Application Note

Determined by its ability to stimulate the proliferation of human microvascular endothelial cells (HMVEC) in low serum

PROPERTIES

Form

Lyophilized powder

Buffer

Batch dependent (please contact us for details)

Storage

Store at -20ºC or below. After reconstitution, keep as concentrated solution. Avoid freeze-thaw cycles.

Region/Sequence

AHYNTEILKS IDNEWRKTQC MPREVCIDVG KEFGVATNTF FKPPCVSVYR CGGCCNSEGL QCMNTSTSYL SKTLFEITVP LSQGPKPVTI SFANHTSCRC MSKLDVYRQV HSIIRR

Expression System

HEK293 cells

Purity

≥ 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin

<0.1 ng/μg of protein (<1EU/μg)

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

vascular endothelial growth factor C , Flt4-L , LMPH1D , LMPHM4 , VRP

Background

The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. The encoded protein promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. The proprotein is further cleaved into a fully processed form that can bind and activate VEGFR-2 and VEGFR-3 receptors. [provided by RefSeq, Apr 2014]

Database

  • Gene ID: 7424 VEGFC

Research Area

REFERENCE

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REVIEW

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