ICAM1 / CD54 antibody [15.2]
Cat. No. GTX20020
Cat. No. GTX20020
This ICAM1 / CD54 antibody [15.2] (GTX20020) is a mouse monoclonal antibody validated for detection of ICAM1 / CD54 by WB, ICC/IF, IHC-P, IHC-Fr, FCM, IP, ELISA, Blocking, and Neutralizing /Inhibition. Reactivity has been shown in Human, Mouse, Rabbit, and other species.
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HostMouse
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ClonalityMonoclonal
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Clone Name15.2
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IsotypeIgG1
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ApplicationsWB ICC/IF IHC-P IHC-Fr FCM IP ELISA Blocking Neutralizing /Inhibition
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ReactivityHuman, Mouse, Rabbit, Pig
Summary
The 15.2 antibody reacts with human CD54, also known as ICAM-1 (Intercellular Adhesion Molecule 1), a 90-110 kDa cell surface glycoprotein that is inducibly expressed on both immune and endothelial cells. As its name implies, ICAM-1 participates in cell-cell adhesion between leukocytes and endothelial cells, facilitating leukocyte recruitment and transmigration at sites of inflammation. The ligands for ICAM-1 are also expressed on leukocyte and endothelial cells, and include Mac-1, fibrinogen, and a member of the integrin αprotein family, LFA-1 (CD11a).