GeneTex
United States (US)

IFNAR2 antibody

GTX105770_40121_IFA_19011506_359.jpg
GTX105770_WB_19011506_945.jpg

Cat No. GTX105770

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
ICC/IF 1:100-1:1000
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

Positive Control

293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human IFNAR2. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

IFN-R antibody, IFN-alpha-REC antibody, IFNABR antibody, IFNARB antibody, IFNAR2 antibody, human interferon alpha/beta receptor antibody, IFN-R-2 antibody, interferon alpha/beta receptor 2 antibody, type I interferon receptor 2 antibody, interferon-alpha/beta receptor beta chain antibody, IFN-alpha binding protein antibody, IFN-alpha/beta receptor 2 antibody, interferon alpha binding protein antibody, "interferon (alpha, beta and omega) receptor 2 antibody"

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene. [provided by RefSeq]

Database

DATA IMAGES
GTX105770_40121_IFA_19011506_359.jpg

GTX105770 ICC/IF Image

Immunofluorescence analysis of methanol-fixed Hep3B, using IFNAR2(GTX105770) antibody at 1:500 dilution.

GTX105770_WB_19011506_945.jpg

GTX105770 WB Image

Sample (30 ug of whole cell lysate)
A: 293T
B: A431 (GTX27909)
7.5% SDS PAGE
GTX105770 diluted at 1:1000

REFERENCE
SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169