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IFNAR2 antibody

Anti-IFNAR2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX105770
Anti-IFNAR2 antibody used in Western Blot (WB). GTX105770

Cat. No. GTX105770

Reference 3

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human
Package
100 μl ($399),
25 μl ($169)
See all IFNAR2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
ICC/IF 1:100-1:1000
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human IFNAR2. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2037220

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

interferon alpha and beta receptor subunit 2 , IFN-R , IFN-alpha-REC , IFNABR , IFNARB , IMD45

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-IFNAR2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX105770

GTX105770 ICC/IF Image

Immunofluorescence analysis of methanol-fixed Hep3B, using IFNAR2(GTX105770) antibody at 1:500 dilution.

Anti-IFNAR2 antibody used in Western Blot (WB). GTX105770

GTX105770 WB Image

Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with IFNAR2 antibody (GTX105770) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

REFERENCE

Application Reference

Yin Y et al. Front Immunol 2022; 13 : 1016982 Pseudorabies virus-induced expression and antiviral activity of type I or type III interferon depend on the type of infected epithelial cell.
Yue Yin et al. J Virol 2021; 95 (20) : e0079321 Pseudorabies Virus Inhibits Type I and Type III Interferon-Induced Signaling via Proteasomal Degradation of Janus Kinases.
Application : WB
Shirozu T et al. J Reprod Dev 2017; 63 (3) : 211-220 estrous cycle stage-dependent manner of type i *-stimulated genes induction in the bovine endometrium.
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REVIEW

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169