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IGF1R antibody [3C8B1]

Anti-IGF1R antibody [3C8B1] used in Western Blot (WB). GTX83067
Anti-IGF1R antibody [3C8B1] used in IHC (Paraffin sections) (IHC-P). GTX83067

Cat. No. GTX83067

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 3C8B1

Isotype

 IgG2b

Application

 WB, IHC-P, ELISA

Reactivity

 Human
Package
100 μl ($399)
See all IGF1R products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
IHC-P 1/200 - 1/1000
ELISA 1/10000
Not tested in other applications.

Calculated MW

155 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of IGF1R-Beta expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

insulin like growth factor 1 receptor , CD221 , IGFIR , IGFR , JTK13

Cellular Localization

Cell membrane

Background

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

Database

Research Area

DATA IMAGES

Anti-IGF1R antibody [3C8B1] used in Western Blot (WB). GTX83067

GTX83067 WB Image

WB analysis of truncated IGF1R-Beta recombinant protein using GTX83067 IGF1R antibody [3C8B1].

Anti-IGF1R antibody [3C8B1] used in IHC (Paraffin sections) (IHC-P). GTX83067

GTX83067 IHC-P Image

IHC-P analysis of human gastric adenocarcinoma(A), colon adenocarcinoma(B), endometrial carcinoma(uterus)(C), ovary adenocarcinoma(D), lung squamous cell carcinoma(E), stomach epithelium mucosae(F) using GTX83067 IGF1R antibody [3C8B1].

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399