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IGF1R antibody [HL1958]

Recombinant antibody
Anti-IGF1R antibody [HL1958] used in Western Blot (WB). GTX637795
Anti-IGF1R antibody [HL1958] used in Western Blot (WB). GTX637795
Anti-IGF1R antibody [HL1958] used in IHC (Paraffin sections) (IHC-P). GTX637795
Anti-IGF1R antibody [HL1958] used in Western Blot (WB). GTX637795

Cat. No. GTX637795

Host

Rabbit

Clonality

Monoclonal

Clone Name

HL1958

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($399),
25 μl ($169)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

155 kDa. ( Note )

Predict Reactivity

Bovine, Pig, Rhesus Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No Preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment of human IGF1R

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

insulin like growth factor 1 receptor , CD221 , IGFIR , IGFR , JTK13

Cellular Localization

Cell membrane

Background

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

Database

Research Area

DATA IMAGES

Anti-IGF1R antibody [HL1958] used in Western Blot (WB). GTX637795

GTX637795 WB Image

Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with IGF1R antibody [HL1958] (GTX637795) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.

Anti-IGF1R antibody [HL1958] used in Western Blot (WB). GTX637795

GTX637795 WB Image

Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with IGF1R antibody [HL1958] (GTX637795) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.

Anti-IGF1R antibody [HL1958] used in IHC (Paraffin sections) (IHC-P). GTX637795

GTX637795 IHC-P Image

IGF1R antibody [HL1958] detects IGF1R protein at cell membrane by immunohistochemical analysis.
Sample: Paraffin-embedded mouse liver.
IGF1R stained by IGF1R antibody [HL1958] (GTX637795) diluted at 1:100.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-IGF1R antibody [HL1958] used in Western Blot (WB). GTX637795

GTX637795 WB Image

Whole cell extract (30 μg) was separated by 5% SDS-PAGE, and the membrane was blotted with IGF1R antibody [HL1958] (GTX637795) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

REFERENCE

There are currently no references for IGF1R antibody [HL1958] (GTX637795). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for IGF1R antibody [HL1958] (GTX637795). Be the first to share your experience with this product.
Package List Price ($)
$ 399
$ 169
Custom Conjugations