APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500-1:3000 |
| Assay dependent |
Not tested in other applications.
Calculated MW
Predict Reactivity
Bovine, Pig, Rhesus Monkey(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
No Preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant fragment of human IGF1R
Purification
Affinity purified by Protein A.
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
insulin like growth factor 1 receptor , CD221 , IGFIR , IGFR , JTK13
Cellular Localization
Cell membrane
Background
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Database
Research Area
DATA IMAGES
![Anti-IGF1R antibody [HL1958] used in Western Blot (WB). GTX637795](/templates/default/js/lightbox/images/loading.gif "Anti-IGF1R antibody [HL1958] used in Western Blot (WB). GTX637795")
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GTX637795 WB Image
Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with IGF1R antibody [HL1958] (GTX637795) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.
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GTX637795 WB Image
Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with IGF1R antibody [HL1958] (GTX637795) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.
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GTX637795 IHC-P Image
IGF1R antibody [HL1958] detects IGF1R protein at cell membrane by immunohistochemical analysis.Sample: Paraffin-embedded mouse liver.IGF1R stained by IGF1R antibody [HL1958] (GTX637795) diluted at 1:100.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
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GTX637795 WB Image
Whole cell extract (30 μg) was separated by 5% SDS-PAGE, and the membrane was blotted with IGF1R antibody [HL1958] (GTX637795) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
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REFERENCE
There are currently no references for IGF1R antibody [HL1958] (GTX637795). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for IGF1R antibody [HL1958] (GTX637795). Be the first to share your experience with this product.
![Anti-IGF1R antibody [HL1958] used in Western Blot (WB). GTX637795](/upload/website/prouct_img/small/GTX637795/GTX637795_T-44851_20221111_WB_M_22111518_666.webp "Anti-IGF1R antibody [HL1958] used in Western Blot (WB). GTX637795")
![Anti-IGF1R antibody [HL1958] used in Western Blot (WB). GTX637795](/upload/website/prouct_img/small/GTX637795/GTX637795_T-44851_20221111_WB_22111518_455.webp "Anti-IGF1R antibody [HL1958] used in Western Blot (WB). GTX637795")
![Anti-IGF1R antibody [HL1958] used in IHC (Paraffin sections) (IHC-P). GTX637795](/upload/website/prouct_img/small/GTX637795/GTX637795_T-44851_20221215_IHC-P_M_22122722_656.webp "Anti-IGF1R antibody [HL1958] used in IHC (Paraffin sections) (IHC-P). GTX637795")
![Anti-IGF1R antibody [HL1958] used in Western Blot (WB). GTX637795](/upload/website/prouct_img/small/GTX637795/GTX637795_44907_20230106_WB_R_23010922_154.webp "Anti-IGF1R antibody [HL1958] used in Western Blot (WB). GTX637795")
![Anti-IGF1R antibody [HL1958] used in Western Blot (WB). GTX637795](/upload/website/prouct_img/normal/GTX637795/GTX637795_T-44851_20221111_WB_M_22111518_666.webp "Anti-IGF1R antibody [HL1958] used in Western Blot (WB). GTX637795")
![Anti-IGF1R antibody [HL1958] used in Western Blot (WB). GTX637795](/upload/website/prouct_img/normal/GTX637795/GTX637795_T-44851_20221111_WB_22111518_455.webp "Anti-IGF1R antibody [HL1958] used in Western Blot (WB). GTX637795")
![Anti-IGF1R antibody [HL1958] used in IHC (Paraffin sections) (IHC-P). GTX637795](/upload/website/prouct_img/normal/GTX637795/GTX637795_T-44851_20221215_IHC-P_M_22122722_656.webp "Anti-IGF1R antibody [HL1958] used in IHC (Paraffin sections) (IHC-P). GTX637795")
![Anti-IGF1R antibody [HL1958] used in Western Blot (WB). GTX637795](/upload/website/prouct_img/normal/GTX637795/GTX637795_44907_20230106_WB_R_23010922_154.webp "Anti-IGF1R antibody [HL1958] used in Western Blot (WB). GTX637795")