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IGF1R antibody

Anti-IGF1R antibody used in Western Blot (WB). GTX25497
Anti-IGF1R antibody used in Western Blot (WB). GTX25497
Anti-IGF1R antibody used in IHC (Paraffin sections) (IHC-P). GTX25497
Anti-IGF1R antibody used in Western Blot (WB). GTX25497

Cat. No. GTX25497

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
400 μl ($399)
See all IGF1R products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
IHC-P 1:50-1:100
Not tested in other applications.

Calculated MW

155 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

This IGF1 Receptor (IGF1R) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1335-1366 amino acids from the C-terminal region of human IGF1 Receptor (IGF1R).

Purification

Purified by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

insulin like growth factor 1 receptor , IGFR , CD221 , IGFIR , JTK13 , IGF1R

Cellular Localization

Cell membrane

Background

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

Database

Research Area

DATA IMAGES

Anti-IGF1R antibody used in Western Blot (WB). GTX25497

GTX25497 WB Image

WB analysis of various cell lysates using GTX25497 IGF1R antibody.
Dilution : 1:2000
Loading : 20 μg per lane

Anti-IGF1R antibody used in Western Blot (WB). GTX25497

GTX25497 WB Image

WB analysis of SK-BR-3 cell lysate using GTX25497 IGF1R antibody.

Anti-IGF1R antibody used in IHC (Paraffin sections) (IHC-P). GTX25497

GTX25497 IHC-P Image

IHC-P analysis of human hepatocarcinoma tissue using GTX25497 IGF1R antibody.

Anti-IGF1R antibody used in Western Blot (WB). GTX25497

GTX25497 WB Image

WB analysis of various cell lysates using GTX25497 IGF1R antibody.
Dilution : 1:2000
Loading : 20 μg per lane

REFERENCE

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REVIEW

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Package List Price ($)
$ 399