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IGF1R (phospho Tyr1131) / Insulin Receptor (phospho Tyr1146) antibody

Anti-IGF1R (phospho Tyr1131) / Insulin Receptor (phospho Tyr1146) antibody used in Western Blot (WB). GTX52315

Cat No. GTX52315

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IP, IHC

Reactivity

Human, Mouse, Rat
Package
100 μg ($319)

APPLICATION

Application Note

WB 1:500-1:2000, IHC 1:50-1:200, IP

Calculated MW

155 kDa. ( Note )

Specificity/Sensitivity

This antibody is raised against a synthetic peptide around phosphorylated Tyr1131 of IGF1R (signal peptide cleaved form), which is identical to the sequence around phosphorylated Tyr1146 of Insulin Receptor (signal peptide cleaved form of P06213-2).

PROPERTIES

Form

Liquid

Buffer

phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human IGF1R around the phosphorylation site of Tyr1161

Purification

Antigen affinity purification

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Insulin Like Growth Factor 1 Receptor , Cd221 , Igfir , Igfr , Jtk13 , Igf1R

Background

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-IGF1R (phospho Tyr1131) / Insulin Receptor (phospho Tyr1146) antibody used in Western Blot (WB). GTX52315

GTX52315 WB Image

Western blot analysis of IGF1R phosphorylation expression in Insulin treated 293 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

REFERENCE

There are currently no references for IGF1R (phospho Tyr1131) / Insulin Receptor (phospho Tyr1146) antibody (GTX52315). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for IGF1R (phospho Tyr1131) / Insulin Receptor (phospho Tyr1146) antibody (GTX52315). Be the first to share your experience with this product.
SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 319