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IGF2BP2 antibody

Anti-IGF2BP2 antibody used in Western Blot (WB). GTX33256
Anti-IGF2BP2 antibody used in IHC (Paraffin sections) (IHC-P). GTX33256
Anti-IGF2BP2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33256

Cat. No. GTX33256

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all IGF2BP2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:200 - 1:2000
ICC/IF 1:50 - 1:100
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

66 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 500 to the C-terminus of human IGF2BP2 (NP_006539.3).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

insulin like growth factor 2 mRNA binding protein 2 , IMP-2 , IMP2 , VICKZ2

Cellular Localization

Nucleus,Cytoplasm

Background

This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes. [provided by RefSeq, Sep 2016]

Database

Research Area

DATA IMAGES

Anti-IGF2BP2 antibody used in Western Blot (WB). GTX33256

GTX33256 WB Image

WB analysis of various sample lysates using GTX33256 IGF2BP2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-IGF2BP2 antibody used in IHC (Paraffin sections) (IHC-P). GTX33256

GTX33256 IHC-P Image

IHC-P analysis of mouse liver tissue using GTX33256 IGF2BP2 antibody.
Dilution : 1:100

Anti-IGF2BP2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33256

GTX33256 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX33256 IGF2BP2 antibody.
Blue : DAPI
Dilution : 1:100

REFERENCE

Application Reference

Weng H et al. Cancer Cell 2022; 40 (12) : 1566-1582.e10 The m(6)A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia.
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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399