APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:1000-5000 |
1:50-1:200 |
1:50-1:200 |
1:50-1:100 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
TBS pH7.4, 1% BSA, 40% Glycerol
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Purification
Protein A purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
Insulin Like Growth Factor 2 Receptor , Cd222 , Ci-M6Pr , Cimpr , M6P-R , M6P/Igf2R , Mpr 300 , Mpr1 , Mpr300 , Mpri , Igf2R
Background
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele. [provided by RefSeq, Apr 2013]
Research Area
DATA IMAGES
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GTX64270 WB Image
Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with IGF2R antibody [GT1078] (GTX64270) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.
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GTX64270 FACS Image
FACS analysis of HeLa cells using GTX64270 IGF2 Receptor antibody [GT1078].
Blue : Primary antibody Red : Isotype control
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GTX64270 ICC/IF Image
ICC/IF analysis of HepG2 cells using GTX64270 IGF2 Receptor antibody [GT1078].
Fixation : 4% PFA
Permeabilization : 0.25% Triton X-100 in PBS
Green : Primary antibody Blue : DAPI
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GTX64270 ICC/IF Image
ICC/IF analysis of MCF-7 cells using GTX64270 IGF2 Receptor antibody [GT1078].
Fixation : 4% PFA
Permeabilization : 0.25% Triton X-100 in PBS
Green : Primary antibody Blue : DAPI
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GTX64270 IHC-P Image
IHC-P analysis of human tonsil tissue using GTX64270 IGF2 Receptor antibody [GT1078].
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GTX64270 ICC/IF Image
ICC/IF analysis of HeLa cells using GTX64270 IGF2 Receptor antibody [GT1078].
Fixation : 4% PFA
Permeabilization : 0.25% Triton X-100 in PBS
Green : Primary antibody Blue : DAPI
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REFERENCE
There are currently no references for IGF2R antibody [GT1078] (GTX64270). Be the first to share your publications with this product.
REVIEW
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