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IKB beta antibody [7B4]

Orthogonal
Anti-IKB beta antibody [7B4] used in Western Blot (WB). GTX82797
Anti-IKB beta antibody [7B4] used in Western Blot (WB). GTX82797
Anti-IKB beta antibody [7B4] used in Western Blot (WB). GTX82797
Anti-IKB beta antibody [7B4] used in Western Blot (WB). GTX82797
Anti-IKB beta antibody [7B4] used in Western Blot (WB). GTX82797

Cat. No. GTX82797

Reference 3

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 7B4

Isotype

 IgG1

Application

 WB, ELISA

Reactivity

 Human, Rat
Package
100 μl ($399)
See all IKB beta products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
ELISA 1/10000
Not tested in other applications.

Calculated MW

38 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human NFKBIB expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

RRID

AB_11163639

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

NFKB inhibitor beta , IKBB , TRIP9

Cellular Localization

Cytoplasm,Nucleus

Background

The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011]

Database

Research Area

DATA IMAGES

Anti-IKB beta antibody [7B4] used in Western Blot (WB). GTX82797

GTX82797 WB Image

WB analysis of Jurkat cell lysate using GTX82797 IKB beta antibody [7B4].

Anti-IKB beta antibody [7B4] used in Western Blot (WB). GTX82797

GTX82797 WB Image

Orthogonal

The data was published in the journal Oncogene in 2019.PMID: 31363162

Anti-IKB beta antibody [7B4] used in Western Blot (WB). GTX82797

GTX82797 WB Image

Orthogonal

The data was published in the journal Oncogene in 2019.PMID: 31363162

Anti-IKB beta antibody [7B4] used in Western Blot (WB). GTX82797

GTX82797 WB Image

Orthogonal

The data was published in the journal Oncogene in 2019.PMID: 31363162

Anti-IKB beta antibody [7B4] used in Western Blot (WB). GTX82797

GTX82797 WB Image

Orthogonal

The data was published in the journal Int J Mol Sci in 2018. PMID: 30314265

REFERENCE

Application Reference

AS Arellano Buendia et al. PeerJ 2023; Antioxidant and anti-inflammatory effects of allicin in the kidney of an experimental model of metabolic syndrome
Hsueh YS et al. Oncogene 2019; 38 (38) : 6550-6565 Nuclear KIT induces a NFKBIB-RELA-KIT autoregulatory loop in imatinib-resistant gastrointestinal stromal tumors.
Arellano Buendia AS et al. Int J Mol Sci 2018; 19 (10) Immunomodulatory Effects of the Nutraceutical Garlic Derivative Allicin in the Progression of Diabetic Nephropathy.
Application : WB
Reactivity : Rat
Submit a Reference

REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399