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IKB beta (phospho Ser23) antibody

Anti-IKB beta (phospho Ser23) antibody used in Western Blot (WB). GTX50317
Anti-IKB beta (phospho Ser23) antibody used in IHC (Paraffin sections) (IHC-P). GTX50317

Cat No. GTX50317

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human
Package
100 μl ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IHC-P 1:50-1:100
Not tested in other applications.

Calculated MW

38 kDa. ( Note )

Predict Reactivity

Mouse, Rat(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH 7.4, 150mM NaCl, 0.02% sodium azide, 50% glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide sequence around phosphorylation site of serine 23 (L-G-S(p)-L-G) derived from human IKB beta.

Purification

Purified by antigen-affinity chromatography. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

NFKB inhibitor beta , IKBB , TRIP9

Cellular Localization

Cytoplasm,Nucleus

Background

The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011]

Database

Research Area

DATA IMAGES

Anti-IKB beta (phospho Ser23) antibody used in Western Blot (WB). GTX50317

GTX50317 WB Image

WB analysis of extracts from HT-29 cells treated with CA or calf intestinal phosphatase (CIP) using GTX50317 IKB beta (phospho Ser23) antibody.

Anti-IKB beta (phospho Ser23) antibody used in IHC (Paraffin sections) (IHC-P). GTX50317

GTX50317 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX50317 IKB beta (phospho Ser23) antibody.
Left : Primary antibody
Right : Primary antibody pre-incubated with the antigen specific peptide

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 319