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IKB beta (phospho Thr19) antibody

Anti-IKB beta (phospho Thr19) antibody used in IHC (Paraffin sections) (IHC-P). GTX32226
Anti-IKB beta (phospho Thr19) antibody used in Western Blot (WB). GTX32226

Cat No. GTX32226

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
IHC-P 1:100 - 1:200
Not tested in other applications.

Calculated MW

38 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.42% Potassium phosphate, 0.87% Sodium chloride pH 7.3, 30% glycerol, 0.01% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of IKB beta. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

NFKB inhibitor beta , IKBB , TRIP9

Cellular Localization

Cytoplasm,Nucleus

Background

The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011]

Database

Research Area

DATA IMAGES

Anti-IKB beta (phospho Thr19) antibody used in IHC (Paraffin sections) (IHC-P). GTX32226

GTX32226 IHC-P Image

IHC-P analysis of formalin fixed human brain tissue section using GTX32226 IKB beta (phospho Thr19) antibody.
Antigen retrieval : Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0)

Anti-IKB beta (phospho Thr19) antibody used in Western Blot (WB). GTX32226

GTX32226 WB Image

WB analysis of LPS-treated Raw264.7 (A), UV-treated PC12 (B), rat brain (C) whole cell lysates using GTX32226 IKB beta (phospho Thr19) antibody.

REFERENCE

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REVIEW

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