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IKB epsilon antibody

Anti-IKB epsilon antibody used in IHC (Paraffin sections) (IHC-P). GTX37290
Anti-IKB epsilon antibody used in Western Blot (WB). GTX37290

Cat. No. GTX37290

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
50 μl ($399)
See all IKB epsilon products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
IHC-P 1:50-1:100
Not tested in other applications.

Calculated MW

53 kDa. ( Note )

Product Note

IkB-epsilon antibody detects endogenous levels of total IkB-epsilon protein.

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized non-phosphopeptide derived from human IkB-epsilon around the phosphorylation site of serine 22 ( I -E-S(p)-L-R).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

NFKB inhibitor epsilon , IKBE

Cellular Localization

Cytoplasm

Background

The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus. [provided by RefSeq, Sep 2011]

Database

Research Area

DATA IMAGES

Anti-IKB epsilon antibody used in IHC (Paraffin sections) (IHC-P). GTX37290

GTX37290 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX37290 IKB epsilon antibody.

Anti-IKB epsilon antibody used in Western Blot (WB). GTX37290

GTX37290 WB Image

WB analysis of HeLa, 293, and HepG2 cells lysates using GTX37290 IKB epsilon antibody.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399