IKK alpha (phospho Ser180) + IKK beta (phospho Ser181) antibody

Cat. No. GTX79040

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	IHC-P
Reactivity	Human
Package	100 μg ($399)

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Datasheet

View product citations for antibody GTX79040 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
IHC-P	1:50 - 1:100

Not tested in other applications.

Calculated MW

85 kDa. ( Note )

Predict Reactivity

Mouse, Rat(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized phosphopeptide derived from human IKKa/b around the phosphorylation site of serine 180/181 (C-T-Sp-F-V ).

Purification

Purified by sequential chromatography on phospho- and non-phospho-peptide affinity columns.
From serum

Conjugation

Unconjugated

RRID

AB_11166523

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CHUK,IKBKA,IKK1,IKKA,IKKalpha,NFKBIKA,TCF16,conserved helixloophelix ubiquitous kinase,IKK alpha,component of inhibitor of nuclear factor kappa B kinase complex

Cellular Localization

Cytoplasm,Nucleus

Background

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]

Database

Gene ID: 1147 CHUK
UniProt: O15111 CHUK

Research Area

DATA IMAGES

GTX79040 IHC-P Image

IHC-P analysis of human skeletal muscle tissue using GTX79040 IKK alpha (phospho Ser180) + IKK beta (phospho Ser181) antibody.

REFERENCE

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REVIEW

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Package

List Price ($)

100 μg

$ 399

Qty