GeneTex
United States (US)

IKK gamma antibody

IKK-gamma-antibody_WB_GTX30263-1_18121411_262.png
IKK-gamma-antibody_ELISA_GTX30263-1_18121411_961.png

Cat No. GTX30263

Host Rabbit
Clonality Polyclonal
Application WB, ELISA
Reactivity Human
APPLICATION

Specificity/Sensitivity

Reacts with residues 385-399 [RRSPPEEPPDFCCPK] of the IKK-g protein. Recognizes both human isoforms.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml(Please refer to the vial label for the specific concentration.)

Immunogen

C-terminus of the IKK-gamma protein (proprietary)

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Background

Pro-inflammatory cytokines activate the transcription factor NF-kappa B by stimulating the activity of a protein kinase that phosphorylates Ikappa B, an inhibitor of NF-kappa B, at sites that trigger its ubiquitination and degradation. A large, cytokine-responsive Ikappa B kinase (IKK) complex has been purified and the genes encoding 2 of its subunits have been cloned. These subunits, IKK-alpha and Ikk-beta, are protein kinases whose function is needed for NF-kappa B activation by pro-inflammatory stimuli. IKK is composed of similar amounts of IKK-alpha, Ikk-beta, which are differentially processed forms of a third subunit, IKK-gamma. Ikk-gamma interacts preferentially with IKK-beta and is required for the activation of the IKK complex.

Research Area

DATA IMAGES
IKK-gamma-antibody_WB_GTX30263-1_18121411_262.png

GTX30263 WB Image

Western blot analysis of IKK-g in Interleukin-1 stimulated 293 cells with anti-IKK-g at a 1:500 dilution.

IKK-gamma-antibody_ELISA_GTX30263-1_18121411_961.png

GTX30263 ELISA Image

Detection of IKK-g using GTX30263 as the capture antibody in ELISA

Package List Price ($)
$ 289