GeneTex
United States (US)

IKZF3 antibody

GTX64869_20180530_WB_18121411_635.jpg
GTX64869_20180530_ICCIF_18121411_666.jpg

Cat No. GTX64869

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:100
Not tested in other applications.

Calculated MW

58 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 280-450 of human IKZF3 (NP_036613.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

AIOLOS Antibody , AIO Antibody , ZNFN1A3 Antibody

Background

This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012]

Database

DATA IMAGES
GTX64869_20180530_WB_18121411_635.jpg

GTX64869 WB Image

WB analysis of various samples using GTX64869 IKZF3 antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX64869_20180530_ICCIF_18121411_666.jpg

GTX64869 ICC/IF Image

ICC/IF analysis of MCF-7 cell using GTX64869 IKZF3 antibody.
Blue : DAPI

Package List Price ($)
$ 319