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IL1 Receptor 2 antibody [4T28]

Cat No. GTX52809

Host

Mouse

Clonality

Monoclonal

Clone Name

4T28

Isotype

IgG2

Application

WB, IHC-Fr, Neutralizing/Inhibition

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-Fr 1:20 - 1:200
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

45 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant IL1-R II EC domain

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD121b , CDw121b , IL1R2 , IL1R2c , IL1RB , IL1RT2 , interleukin 1 receptor type 2 , IL1 Receptor 2 , IL1 Receptor II , IL-1RII

Cellular Localization

Secreted,Cell membrane

Background

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012]

Database

Research Area

REFERENCE

There are currently no references for IL1 Receptor 2 antibody [4T28] (GTX52809). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for IL1 Receptor 2 antibody [4T28] (GTX52809). Be the first to share your experience with this product.
SDS
PBS.pdf