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IL1 Receptor antagonist antibody

Anti-IL1 Receptor antagonist antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32673
Anti-IL1 Receptor antagonist antibody used in Western Blot (WB). GTX32673

Cat No. GTX32673

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human, Mouse
Package
100 μl ($329)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

20 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-159 of human IL1RN (NP_000568.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

interleukin 1 receptor antagonist , DIRA , ICIL-1RA , IL-1RN , IL-1ra , IL-1ra3 , IL1F3 , IL1RA , IRAP , MVCD4

Background

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jan 2016]

Database

Research Area

DATA IMAGES
Anti-IL1 Receptor antagonist antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32673

GTX32673 ICC/IF Image

ICC/IF analysis of MCF-7 cell using GTX32673 IL1 Receptor antagonist antibody.
Blue : DAPI

Anti-IL1 Receptor antagonist antibody used in Western Blot (WB). GTX32673

GTX32673 WB Image

WB analysis of various samples using GTX32673 IL1 Receptor antagonist antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE
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REVIEW
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