GeneTex
United States (US)

IL1 beta antibody [ILB1-H6] (Biotin)

GTX15755_58_ELISA_19011519_125.jpg

Cat No. GTX15755

Host Mouse
Clonality Monoclonal
Clone Name ILB1-H6
Isotype IgG1
Application ELISA, sELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ELISA Assay dependent
sELISA Assay dependent

Note :

sELISA
Capture : GTX15756, Detection : GTX15755

Not tested in other applications.

Calculated MW

31 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS, 4% BSA, proprietary preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human IL-1 beta

Purification

Protein G purified

Conjugation

Biotin

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Interleukin 1 Beta,Il-1,Il1-Beta,Il1F2,Il1B

Cellular Localization

Cytoplasm,Cytosol,Exosome,Lysosome,Secreted

Background

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX15755_58_ELISA_19011519_125.jpg

GTX15755 ELISA Image

Sandwich ELISA analysis of serial diluted human IL-1b recombinant protein(50ul per well) using IL1 beta antibody [ILB1-H6]
Coating : GTX15756 IL1 beta antibody [ILB1-H67](5 µg/mL)
Detection : GTX15755 IL1 beta antibody [ILB1-H6] (Biotin) (0.07 µg/mL)