IL1 beta antibody [ILB1-H67]

Cat. No. GTX15756

Host	Mouse
Clonality	Monoclonal
Clone Name	ILB1-H67
Isotype	IgG2b
Application	WB, ICC/IF, ELISA, IHC, Sandwich ELISA
Reactivity	Human
Package	250 μg ($399)

See all IL1 beta products

Datasheet
Document

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	Assay dependent
ICC/IF	Assay dependent
ELISA	Assay dependent
IHC	Assay dependent
Sandwich ELISA	Assay dependent
Note : Sandwich ELISA Capture : GTX15756, Detection : GTX15755

Not tested in other applications.

Calculated MW

31 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.79 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human IL-1 beta

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

interleukin 1 beta , IL-1 , IL1-BETA , IL1F2

Cellular Localization

Cytoplasm, cytosol,Lysosome,Secreted

Background

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]

Database

Gene ID: 3553 IL1B
UniProt: P01584 IL1B

Research Area

DATA IMAGES

GTX15756 ELISA Image

Sandwich ELISA analysis of serial diluted human IL-1b recombinant protein(50ul per well) using IL1 beta antibody [ILB1-H6]
Coating : GTX15756 IL1 beta antibody [ILB1-H67](5 μg/mL)
Detection : GTX15755 IL1 beta antibody [ILB1-H6] (Biotin) (0.07 μg/mL)

REFERENCE

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REVIEW

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SDS
PBS.pdf

Package

List Price ($)

250 μg

$ 399

Qty Custom Conjugations

IL1 beta antibody [ILB1-H67]

Cat. No. GTX15756

Host

Clonality

Clone Name

Isotype

Application

Reactivity