IL1 beta antibody [ILB1-H67]

Cat No. GTX15756

Host	Mouse
Clonality	Monoclonal
Clone Name	ILB1-H67
Isotype	IgG2b
Application	WB, ICC/IF, ELISA, IHC, sELISA
Reactivity	Human

See all IL1 beta products

Datasheet
Document

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
WB	Assay dependent
ICC/IF	Assay dependent
ELISA	Assay dependent
IHC	Assay dependent
sELISA	Assay dependent
Note : sELISA Capture : GTX15756, Detection : GTX15755

Not tested in other applications.

Calculated MW

31 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.79 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human IL-1 beta

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Interleukin 1 Beta,Il-1,Il1-Beta,Il1F2,Il1B

Cellular Localization

Cytoplasm,Cytosol,Exosome,Lysosome,Secreted

Background

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]

Database

Gene ID: 3553
UniProt: P01584

Research Area

DATA IMAGES

GTX15756 ELISA Image

Sandwich ELISA analysis of serial diluted human IL-1b recombinant protein(50ul per well) using IL1 beta antibody [ILB1-H6]
Coating : GTX15756 IL1 beta antibody [ILB1-H67](5 µg/mL)
Detection : GTX15755 IL1 beta antibody [ILB1-H6] (Biotin) (0.07 µg/mL)