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IL1 beta antibody [MT175]

Anti-IL1 beta antibody [MT175] used in ELISA (ELISA). GTX02972

Cat. No. GTX02972

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MT175

Isotype

 IgG1

Application

 ELISA, Sandwich ELISA

Reactivity

 Human
Package
250 μg ($399)
See all IL1 beta products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ELISA Assay dependent
Sandwich ELISA Assay dependent

Note :

Sandwich ELISA
Capture: GTX02972, Detection: GTX02971-02.
Not tested in other applications.

Calculated MW

31 kDa. ( Note )

Product Note

This antibody is able to detect native and recombinant human IL-1β, binds to the pro-form and active form of IL-1β, and has no cross-reactivity with IL-1α.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human IL-1β

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

IL1,IL1B,IL1BETA,IL1F2,interleukin 1 beta,IL1 beta,IL-1B

Cellular Localization

Cytoplasm,Cytosol,Lysosome,Secreted,Exosome

Background

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-IL1 beta antibody [MT175] used in ELISA (ELISA). GTX02972

GTX02972 ELISA Image

Sandwich ELISA analysis of human IL-1 beta protein using GTX02972 IL1 beta antibody [MT175] as coating antibody and GTX02971-02 IL1 beta antibody [7P10] (Biotin) as detecting antibody.
Substrate : pNPP

REFERENCE

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REVIEW

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Package List Price ($)
$ 399