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IL10 antibody [3C12C12]

Anti-IL10 antibody [3C12C12] used in Western Blot (WB). GTX83241

Cat No. GTX83241

Host

Mouse

Clonality

Monoclonal

Clone Name

3C12C12

Isotype

IgG1

Application

WB, ELISA

Reactivity

Human
Package
100 μl ($379)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1/500 - 1/2000
ELISA 1/10000
Not tested in other applications.

Calculated MW

21 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human IL-10 expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

interleukin 10 , CSIF , GVHDS , IL-10 , IL10A , TGIF

Cellular Localization

Secreted

Background

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]

Database

Research Area

DATA IMAGES

Anti-IL10 antibody [3C12C12] used in Western Blot (WB). GTX83241

GTX83241 WB Image

WB analysis of IL10 recombinant protein using GTX83241 IL10 antibody [3C12C12].

REFERENCE

There are currently no references for IL10 antibody [3C12C12] (GTX83241). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for IL10 antibody [3C12C12] (GTX83241). Be the first to share your experience with this product.
SDS
Sodium Azide.pdf
Package List Price ($)
$ 379