APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Dilution |
| 1-2 μg/ml |
|
Note :
IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA (pH 9.0) for 45 min at 95ºC followed by cooling at RT for 20 minutes.
|
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
10mM PBS, 0.05% BSA
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Concentration
200 μg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant full-length human Interleukin 10 (IL10) protein
Purification
Protein A purified
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
interleukin 10 , CSIF , GVHDS , IL-10 , IL10A , TGIF
Cellular Localization
Secreted
Background
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]
Database
Research Area
DATA IMAGES
![Anti-IL10 antibody [IL10/2651R] used in IHC (Paraffin sections) (IHC-P). GTX02650](/templates/default/js/lightbox/images/loading.gif "Anti-IL10 antibody [IL10/2651R] used in IHC (Paraffin sections) (IHC-P). GTX02650")
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GTX02650 IHC-P Image
IHC-P analysis of human endocervical carcinoma section using GTX02650 IL10 antibody [IL10/2651R].
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GTX02650 IHC-P Image
IHC-P analysis of human prostate carcinoma section using GTX02650 IL10 antibody [IL10/2651R].
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REFERENCE
There are currently no references for IL10 antibody [IL10/2651R] (GTX02650). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for IL10 antibody [IL10/2651R] (GTX02650). Be the first to share your experience with this product.
![Anti-IL10 antibody [IL10/2651R] used in IHC (Paraffin sections) (IHC-P). GTX02650](/upload/website/prouct_img/small/GTX02650/GTX02650_20210319_IHC-P_21031902_653.jpg "Anti-IL10 antibody [IL10/2651R] used in IHC (Paraffin sections) (IHC-P). GTX02650")
![Anti-IL10 antibody [IL10/2651R] used in IHC (Paraffin sections) (IHC-P). GTX02650](/upload/website/prouct_img/small/GTX02650/GTX02650_20210319_IHC-P_1_21031902_957.jpg "Anti-IL10 antibody [IL10/2651R] used in IHC (Paraffin sections) (IHC-P). GTX02650")
![Anti-IL10 antibody [IL10/2651R] used in IHC (Paraffin sections) (IHC-P). GTX02650](/upload/website/prouct_img/normal/GTX02650/GTX02650_20210319_IHC-P_21031902_653.jpg "Anti-IL10 antibody [IL10/2651R] used in IHC (Paraffin sections) (IHC-P). GTX02650")
![Anti-IL10 antibody [IL10/2651R] used in IHC (Paraffin sections) (IHC-P). GTX02650](/upload/website/prouct_img/normal/GTX02650/GTX02650_20210319_IHC-P_1_21031902_957.jpg "Anti-IL10 antibody [IL10/2651R] used in IHC (Paraffin sections) (IHC-P). GTX02650")