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IL10 antibody [IL10/2651R]

Anti-IL10 antibody [IL10/2651R] used in IHC (Paraffin sections) (IHC-P). GTX02650
Anti-IL10 antibody [IL10/2651R] used in IHC (Paraffin sections) (IHC-P). GTX02650

Cat. No. GTX02650

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 IL10/2651R

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
100 μg ($529)
See all IL10 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1-2 μg/ml

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA (pH 9.0) for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

21 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full-length human Interleukin 10 (IL10) protein

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

interleukin 10 , CSIF , GVHDS , IL-10 , IL10A , TGIF

Cellular Localization

Secreted

Background

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]

Database

Research Area

DATA IMAGES

Anti-IL10 antibody [IL10/2651R] used in IHC (Paraffin sections) (IHC-P). GTX02650

GTX02650 IHC-P Image

IHC-P analysis of human endocervical carcinoma section using GTX02650 IL10 antibody [IL10/2651R].

Anti-IL10 antibody [IL10/2651R] used in IHC (Paraffin sections) (IHC-P). GTX02650

GTX02650 IHC-P Image

IHC-P analysis of human prostate carcinoma section using GTX02650 IL10 antibody [IL10/2651R].

REFERENCE

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REVIEW

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Package List Price ($)
$ 529