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IL10 antibody, Internal

Anti-IL10 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX80555
Anti-IL10 antibody, Internal used in Western Blot (WB). GTX80555
Anti-IL10 antibody, Internal used in Flow cytometry (FACS). GTX80555

Cat. No. GTX80555

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, FACS

Reactivity

 Human
Package
400 μl ($399)
See all IL10 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
IHC-P 1:10-1:50
FACS 1:10-1:50
Not tested in other applications.

Calculated MW

21 kDa. ( Note )

Predict Reactivity

Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 27-53 amino acids from the Central region of human IL10.

Purification

Protein A purified, followed by peptide affinity purification.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

interleukin 10 , CSIF , GVHDS , IL-10 , IL10A , TGIF

Cellular Localization

Secreted

Background

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]

Database

Research Area

DATA IMAGES

Anti-IL10 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX80555

GTX80555 IHC-P Image

IHC-P analysis of human breast carcinoma using GTX80555 IL10 antibody, Internal.

Anti-IL10 antibody, Internal used in Western Blot (WB). GTX80555

GTX80555 WB Image

WB analysis of MDA-MB435 cell lysate (35ug/lane) using GTX80555 IL10 antibody, Internal.

Anti-IL10 antibody, Internal used in Flow cytometry (FACS). GTX80555

GTX80555 FACS Image

FACS analysis of Jurkat cells using GTX80555 IL10 antibody, Internal.
Top histogram : negative control
Bottom histogram : Jurkat cells

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399