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IL12B / IL12 p40 antibody [C17-8] (Biotin)

Anti-IL12B / IL12 p40 antibody [C17-8] (Biotin) used in ELISA (ELISA). GTX41390

Cat. No. GTX41390

Reference 1

Host

 Rat

Clonality

 Monoclonal

Clone Name

 C17-8

Isotype

 IgG2a

Application

 FACS, ELISA, ELISPOT

Reactivity

 Mouse
Package
100 μg ($339)
See all IL12B / IL12 p40 products

APPLICATION

Application Note

ELISA: Use at a concentration of 0.25 - 1 μg/ml. ELISPOT: Use at a concentration of 0.5 - 2 μg/ml. FACS: Use at an assay dependent dilution, for intracellular staining. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

38 kDa. ( Note )

Product Note

Recognises IL12 p40 subunit (monomer, dimer and heterodimer with p35).

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.9% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

CHO expressed, recombinant mouse IL12 p70

Purification

Protein A purified

Conjugation

Biotin

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

interleukin 12b , Il-12b , Il-12p40 , Il12p40 , p40

Cellular Localization

Secreted

Background

This gene encodes the beta subunit p40 of the Interleukin 12 (IL-12) family of cytokines. Members of the IL-12 family form heterodimers consisting of heavy and light subunits linked by disulfide bonds. The product of this gene, p40, is a subunit of interleukins IL-12 and IL-23. [provided by RefSeq, Dec 2014]

Database

Research Area

DATA IMAGES

Anti-IL12B / IL12 p40 antibody [C17-8] (Biotin) used in ELISA (ELISA). GTX41390

GTX41390 ELISA Image

Serial dilutions of ELISA detection IL-12 recombinant protein antibody (GTX41390) ranging from 250 to 2 pg/ml were used to obtain a linear standard curve.

REFERENCE

Clone Reference

Su Y et al. Clin Exp Immunol 2017; (Epub) Withasteroid B from D. metel L. Regulates Immune Responses by Modulating the JAK/STAT Pathway and the IL-17+ RORγt+ /IL-10+ FoxP3+ Ratio.
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339