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IL12B / IL12 p40 antibody [MT618] (Biotin)

Anti-IL12B / IL12 p40 antibody [MT618] (Biotin) used in ELISA (ELISA). GTX02956-02

Cat. No. GTX02956-02

Host

Mouse

Clonality

Monoclonal

Clone Name

MT618

Isotype

IgG1

Application

ELISA, Sandwich ELISA

Reactivity

Human, Monkey
Package
250 μg ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ELISA Assay dependent
Sandwich ELISA Assay dependent

Note :

Sandwich ELISA
Capture: GTX02957, Detection: GTX02956-02 (MT618 for p40) / GTX03013-02 (MT704 for p70) / GTX02983-02.

Not tested in other applications.

Calculated MW

37 kDa. ( Note )

Product Note

This antibody is able to detect native and recombinant human p40 subunit of IL-12 and IL-23. In combination with MT86/221, it is able to recognize p40 monomer, p40 homodimer, IL-12 p70 heterodimer (p40 + p35) and IL-23 heterodimer (p40 + p19).

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human IL-23

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Biotin
Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CLMF,CLMF2,IL12B,IMD28,IMD29,NKSF,NKSF2,interleukin 12B,IL12 p40

Cellular Localization

Secreted

Background

This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-IL12B / IL12 p40 antibody [MT618] (Biotin) used in ELISA (ELISA). GTX02956-02

GTX02956-02 ELISA Image

Sandwich ELISA analysis of human IL-12/-23 (p40) protein using GTX02957 IL12B / IL12 p40 antibody [MT86 + MT221] as coating antibody and GTX02956-02 IL12B / IL12 p40 antibody [MT618] (Biotin) as detecting antibody.
Substrate : pNPP

REFERENCE

There are currently no references for IL12B / IL12 p40 antibody [MT618] (Biotin) (GTX02956-02). Be the first to share your publications with this product.

REVIEW

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Package List Price ($)
$ 399