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IL15 Receptor alpha antibody [5M53]

Cat No. GTX52822

Host

Mouse

Clonality

Monoclonal

Clone Name

5M53

Isotype

IgG2

Application

WB

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
Not tested in other applications.

Calculated MW

28 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant IL-15R α EC domain

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD215 , IL15RA , interleukin 15 receptor subunit alpha , IL15 Receptor alpha

Cellular Localization

Membrane,Nucleus membrane,Endoplasmic reticulum membrane,Golgi apparatus membrane,Cytoplasmic vesicle membrane,Secreted,Extracellular space

Background

This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.[provided by RefSeq, Apr 2010]

Database

Research Area

REFERENCE

There are currently no references for IL15 Receptor alpha antibody [5M53] (GTX52822). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for IL15 Receptor alpha antibody [5M53] (GTX52822). Be the first to share your experience with this product.
SDS
PBS.pdf