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IL15 antibody

Anti-IL15 antibody used in IHC (Paraffin sections) (IHC-P). GTX74169
Anti-IL15 antibody used in IHC (Paraffin sections) (IHC-P). GTX74169
Anti-IL15 antibody used in IHC (Paraffin sections) (IHC-P). GTX74169

Cat No. GTX74169

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, IP, ELISA, Neutralizing/Inhibition

Reactivity

Human
Package
50 μg ($359)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.1-0.2μg/ml
IHC-P Assay dependent
IP Assay dependent
ELISA 0.5μg/ml
Neutralizing/Inhibition Assay dependent

Note :

Neutralizing/Inhibition
Rabbit anti Human Interleukin-15 antibody will neutralise IL-15 activity in bioassay systems.

Not tested in other applications.

Calculated MW

18 kDa. ( Note )

Specificity/Sensitivity

This antibody will neutralise IL-15 activity in bioassay systems.

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human IL-15

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Interleukin 15 , Il-15 , Il15

Background

The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Feb 2011]

Database

Research Area

DATA IMAGES

Anti-IL15 antibody used in IHC (Paraffin sections) (IHC-P). GTX74169

GTX74169 IHC-P Image

IHC-P analysis of normal human placenta tissue using GTX74169 IL15 antibody.

Anti-IL15 antibody used in IHC (Paraffin sections) (IHC-P). GTX74169

GTX74169 IHC-P Image

IHC-P analysis of normal human placenta tissue using GTX74169 IL15 antibody.

Anti-IL15 antibody used in IHC (Paraffin sections) (IHC-P). GTX74169

GTX74169 IHC-P Image

IHC-P analysis of normal human placenta tissue using GTX74169 IL15 antibody.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 359