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IL18 Receptor 1 antibody [8H22]

Cat No. GTX52834

Host

Mouse

Clonality

Monoclonal

Clone Name

8H22

Isotype

IgG1

Application

WB, IHC-P, Neutralizing/Inhibition

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:20 - 1:100
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

62 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant IL-18Rα EC domain

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD218a , CDw218a , IL18R1 , IL18RA , IL1RRP , IL1Rrp , interleukin 18 receptor 1 , IL18 Receptor 1 , IL18 Receptor alpha

Cellular Localization

Membrane

Background

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

Database

Research Area

REFERENCE

There are currently no references for IL18 Receptor 1 antibody [8H22] (GTX52834). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for IL18 Receptor 1 antibody [8H22] (GTX52834). Be the first to share your experience with this product.
SDS
PBS.pdf
Package List Price ($)
$ 329