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IL18BP antibody

Anti-IL18BP antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32676
Anti-IL18BP antibody used in IHC (Paraffin sections) (IHC-P). GTX32676
Anti-IL18BP antibody used in Western Blot (WB). GTX32676

Cat No. GTX32676

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P
Reactivity Human, Mouse
Package
100 μl ($329)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:100
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

21 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 31-194 of human IL18BP (NP_001138529.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

interleukin 18 binding protein , IL18BPa

Cellular Localization

Secreted

Background

The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]

Database

Research Area

DATA IMAGES
Anti-IL18BP antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32676

GTX32676 ICC/IF Image

ICC/IF analysis of A549 cell using GTX32676 IL18BP antibody.
Blue : DAPI

Anti-IL18BP antibody used in IHC (Paraffin sections) (IHC-P). GTX32676

GTX32676 IHC-P Image

IHC-P analysis of mouse heart tissue using GTX32676 IL18BP antibody.
Dilution : 1:100

Anti-IL18BP antibody used in Western Blot (WB). GTX32676

GTX32676 WB Image

WB analysis of various samples using GTX32676 IL18BP antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE
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REVIEW
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