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IL2 Receptor alpha antibody [EP218]

Cat No. GTX01625

Host

Rabbit

Clonality

Monoclonal

Clone Name

EP218

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
500 μl ($369)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:50-1:100

Note :

IHC-P
Pretreatment of deparaffinized tissue with heat-induced epitope retrieval or enzymatic retrieval is recommended.

Not tested in other applications.

Calculated MW

31 kDa. ( Note )

Positive Control

Tonsil or lymph node

PROPERTIES

Form

Liquid

Buffer

Tris-HCl buffer, 0.2% BSA, < 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide to human CD25

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

interleukin 2 receptor subunit alpha , CD25 , IDDM10 , IL2R , IMD41 , TCGFR , p55

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]

Database

Research Area

REFERENCE

REVIEW

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Package List Price ($)
$ 369