GeneTex

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United States (US)

IL2 antibody

Cat. No. GTX10751

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, ELISA, Neutralizing/Inhibition

Reactivity

 Human
Package
25 μg ($399)
See all IL2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
ELISA Assay dependent
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

18 kDa. ( Note )

Product Note

The antibody will neutralize the biological activity of recombinant and natural human IL-2. The antibody shows <10% cross reactivity with recombinant mouse and rat IL-2.

PROPERTIES

Form

Liquid

Buffer

PBS carbohydrates

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

recombinant human IL-2.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

interleukin 2 , IL-2 , TCGF , lymphokine

Cellular Localization

Secreted

Background

Interleukin 2 (IL2), also known as T Cell Growth Factor, is an immunomodulatory factor produced by certain subsets of T lymphocytes. This lymphokine is useful in promoting long term growth of activated T cells, B lymphocytes, lymphokine-activated killer (LAK) cells, monocytes, macrophages and oligodendrocytes. Interleukin 2 affects the activation and proliferation of NK cells, induces gamma-interferon and B cell growth factor secretion, and modulates the expression of the IL2 receptor. IL2 also functions as a growth inhibitor in certain neoplastic cells. Multiple biological functions of IL2 have been described including B cell growth and differentiation. Interleukin 2 has been isolated from a number of cell types.

Database

Research Area

REFERENCE

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SDS
PBS.pdf
Package List Price ($)
$ 399