APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
Assay dependent |
Assay dependent |
Assay dependent |
Assay dependent |
Not tested in other applications.
Calculated MW
Product Note
The antibody will neutralize the biological activity of recombinant and natural human IL-2. The antibody shows <10% cross reactivity with recombinant mouse and rat IL-2.
PROPERTIES
Form
Liquid
Buffer
PBS carbohydrates
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
recombinant human IL-2.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
interleukin 2 , IL-2 , TCGF , lymphokine
Cellular Localization
Secreted
Background
Interleukin 2 (IL2), also known as T Cell Growth Factor, is an immunomodulatory factor produced by certain subsets of T lymphocytes. This lymphokine is useful in promoting long term growth of activated T cells, B lymphocytes, lymphokine-activated killer (LAK) cells, monocytes, macrophages and oligodendrocytes. Interleukin 2 affects the activation and proliferation of NK cells, induces gamma-interferon and B cell growth factor secretion, and modulates the expression of the IL2 receptor. IL2 also functions as a growth inhibitor in certain neoplastic cells. Multiple biological functions of IL2 have been described including B cell growth and differentiation. Interleukin 2 has been isolated from a number of cell types.
Database
Research Area
REFERENCE
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REVIEW
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