GeneTex
United States (US)

IL21 Receptor antibody

GTX31270_87_IHC-P_20180221_18121410_448.jpg
GTX31270_877_IHC-P_20180221_18121410_957.jpg
GTX31270_2473_WB_20180221_18121410_374.jpg

Cat No. GTX31270

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 10 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

59 kDa. ( Note )

Positive Control

Raji Cell Lysate(GTX27908) , Rat Lung Tissue Lysate(GTX27941)
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

IL-21 receptor antibody was raised against a synthetic peptide corresponding to amino acids 97 to 111 of human IL-21 receptor precursor.The immunogen is located within amino acids 80 - 130 of IL-21 Receptor.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Interleukin 21 Receptor,Cd360,Imd56,Nilr,Il21R

Background

The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]

Database

Research Area

DATA IMAGES
GTX31270_87_IHC-P_20180221_18121410_448.jpg

GTX31270 IHC-P Image

IHC-P analysis of rat lung tissue using GTX31270 IL21 Receptor antibody.
Working concentration : 20 μg/ml

GTX31270_877_IHC-P_20180221_18121410_957.jpg

GTX31270 IHC-P Image

IHC-P analysis of rat lung tissue using GTX31270 IL21 Receptor antibody.
Working concentration : 10 μg/ml

GTX31270_2473_WB_20180221_18121410_374.jpg

GTX31270 WB Image

WB analysis of HepG2 cell lysate using GTX31270 IL21 Receptor antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

Package List Price ($)
$ 329