APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1 μg/mL |
| 20 μg/mL |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Raji Cell Lysate(GTX27908)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
IL-21 receptor antibody was raised against a synthetic peptide corresponding to amino acids 20 to 32 of human IL-21 receptor precursor.The immunogen is located within the first 50 amino acids of IL-21 Receptor.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
interleukin 21 receptor , CD360 , IMD56 , NILR
Cellular Localization
Membrane; Single-pass type I membrane protein
Background
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
Database
Research Area
DATA IMAGES
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GTX31271 ICC/IF Image
ICC/IF analysis of A431 cells using GTX31271 IL21 Receptor antibody.
Working concentration : 20 μg/ml
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GTX31271 WB Image
WB analysis of Raji cell lysate using GTX31271 IL21 Receptor antibody.
Working concentration : 1 μg/ml
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REFERENCE
There are currently no references for IL21 Receptor antibody (GTX31271). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for IL21 Receptor antibody (GTX31271). Be the first to share your experience with this product.
