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IL21 antibody

Anti-IL21 antibody used in Immunohistochemistry (IHC). GTX82914

Cat. No. GTX82914

Reference 1

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P, ELISA, IHC

Reactivity

 Human
Package
50 μg ($399)
See all IL21 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P Assay dependent
ELISA 1:50,000
IHC 1:250
Not tested in other applications.

Calculated MW

18 kDa. ( Note )

Product Note

Peptide sequence is < 50 % identical to other interleukins in this region and is therefore not expected to cross-react.

PROPERTIES

Form

Liquid

Buffer

10mM KHPO₄, 140mM NaCl, 0.1% BSA

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide C-40RQLIDIVDQLKNYVNDLVPEFLPAPEDVE68 corresponding to N-terminus region of human IL-21

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_625935

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CVID11,IL21,Za11,interleukin 21

Cellular Localization

Secreted

Background

This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Database

Research Area

DATA IMAGES

Anti-IL21 antibody used in Immunohistochemistry (IHC). GTX82914

GTX82914 IHC Image

IHC analysis of human tonsil tissue using GTX82914 IL21 antibody.

REFERENCE

Application Reference

Yang H et al. Mol Med Rep. 2017; (Epub) Frequency and distribution of CD4+CXCR5+ follicular B helper T cells within involved tissues in IgG4-related ophthalmic disease.
Application : IHC-P
Reactivity : Human
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Package List Price ($)
$ 399