APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Dilution |
| 1/500 |
| 1/125 |
|
Note :
IHC-P
This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.
|
Not tested in other applications.
Calculated MW
Product Note
This antibody recognizes an epitope within the N-terminal region of Interleukin-23 receptor, precsent in isoforms 1, 3 and 4 (UniProt: Q5VWK5), the antibody is not expected to recognize other truncated forms of the receptor lacking the immunogen sequence.
PROPERTIES
Form
Liquid
Buffer
PBS, 0.1% BSA
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1.0 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic peptide CQPRKLHFYKNGIKERFQITRINKTTARL corresponding to amino acids 59-87 within the N-terminal region of human IL-23 receptor.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
interleukin 23 receptor
Cellular Localization
Cell membrane
Background
The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX39947 IHC-P Image
IHC-P analysis of human spleen tissue using GTX39947 IL23 Receptor antibody, N-term.
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GTX39947 IHC-P Image
IHC-P analysis of mouse spleen tissue using GTX39947 IL23 Receptor antibody, N-term.
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REFERENCE
There are currently no references for IL23 Receptor antibody, N-term (GTX39947). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for IL23 Receptor antibody, N-term (GTX39947). Be the first to share your experience with this product.
