GeneTex
United States (US)

IL23 Receptor antibody, N-term

GTX39947_4066_IHC-P_18121410_896.jpg
GTX39947_4067_IHC-P_18121410_974.jpg

Cat No. GTX39947

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1/500
IHC-P 1/125

Note :

This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.
Not tested in other applications.

Calculated MW

72 kDa kDa. ( Note )

Specificity/Sensitivity

This antibody recognizes an epitope within the N-terminal region of Interleukin-23 receptor, precsent in isoforms 1, 3 and 4 (UniProt: Q5VWK5), the antibody is not expected to recognize other truncated forms of the receptor lacking the immunogen sequence.
PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% Sodium Azide, 0.1% BSA

Concentration

1.0mg/ml

Antigen Species

Human

Immunogen

Synthetic peptide CQPRKLHFYKNGIKERFQITRINKTTARL corresponding to amino acids 59-87 within the N-terminal region of human IL-23 receptor.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

IL-23R Antibody , IL23R Antibody

Background

The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. [provided by RefSeq, Jul 2008]
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Database

Research Area

DATA IMAGES
GTX39947_4066_IHC-P_18121410_896.jpg

GTX39947 IHC-P Image

IHC-P analysis of human spleen tissue using GTX39947 IL23 Receptor antibody, N-term.

GTX39947_4067_IHC-P_18121410_974.jpg

GTX39947 IHC-P Image

IHC-P analysis of mouse spleen tissue using GTX39947 IL23 Receptor antibody, N-term.