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IL23 Receptor antibody, N-term

Anti-IL23 Receptor antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX39947
Anti-IL23 Receptor antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX39947

Cat. No. GTX39947

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μg ($519)
See all IL23 Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500
IHC-P 1/125

Note :

IHC-P
This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.
Not tested in other applications.

Calculated MW

72 kDa. ( Note )

Product Note

This antibody recognizes an epitope within the N-terminal region of Interleukin-23 receptor, precsent in isoforms 1, 3 and 4 (UniProt: Q5VWK5), the antibody is not expected to recognize other truncated forms of the receptor lacking the immunogen sequence.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide CQPRKLHFYKNGIKERFQITRINKTTARL corresponding to amino acids 59-87 within the N-terminal region of human IL-23 receptor.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

interleukin 23 receptor

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-IL23 Receptor antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX39947

GTX39947 IHC-P Image

IHC-P analysis of human spleen tissue using GTX39947 IL23 Receptor antibody, N-term.

Anti-IL23 Receptor antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX39947

GTX39947 IHC-P Image

IHC-P analysis of mouse spleen tissue using GTX39947 IL23 Receptor antibody, N-term.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 519