GeneTex
United States (US)

IL27 Receptor alpha antibody

GTX54076_4068_IHC-P_18121410_160.jpg
GTX54076_4069_WB_18121410_205.jpg

Cat No. GTX54076

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.5-1μg/ml
ICC/IF 20μg/ml
IHC-P 5μg/ml

Note :

IHC-P
This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose.

Not tested in other applications.

Calculated MW

69 kDa. ( Note )

Specificity/Sensitivity

This antibody recognizes the carboxy terminal of the alpha subunit of the human IL-27 receptor, otherwise known as the T cell cytokine receptor (TCCR).
PROPERTIES

Form

Liquid

Buffer

PBS, 0.02% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A peptide corresponding to amino acids near the carboxy terminus of human IL-27Rα precursor.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

IL-27RA Antibody , IL27R Antibody , WSX1 Antibody , CRL1 Antibody , interleukin 27 receptor, alpha Antibody , zcytor1 Antibody , IL27RA Antibody

Background

In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES
GTX54076_4068_IHC-P_18121410_160.jpg

GTX54076 IHC-P Image

IHC analysis of human spleen tissue using GTX54076 IL27 Receptor alpha antibody.

GTX54076_4069_WB_18121410_205.jpg

GTX54076 WB Image

WB analysis of human spleen tissue lysate using GTX54076 IL27 Receptor alpha antibody.

Package List Price ($)
$ 329