APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 0.5-1μg/ml |
| 20μg/ml |
| 5μg/ml |
|
Note :
IHC-P
This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose.
|
Not tested in other applications.
Calculated MW
Product Note
This antibody recognizes the carboxy terminal of the alpha subunit of the human IL-27 receptor, otherwise known as the T cell cytokine receptor (TCCR).
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A peptide corresponding to amino acids near the carboxy terminus of human IL-27Rα precursor.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
interleukin 27 receptor subunit alpha , CRL1 , IL-27RA , IL27R , TCCR , WSX1 , zcytor1
Cellular Localization
Membrane; Single-pass type I membrane protein
Background
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX54076 WB Image
WB analysis of human spleen tissue lysate using GTX54076 IL27 Receptor alpha antibody.
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GTX54076 IHC-P Image
IHC analysis of human spleen tissue using GTX54076 IL27 Receptor alpha antibody.
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REFERENCE
There are currently no references for IL27 Receptor alpha antibody (GTX54076). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for IL27 Receptor alpha antibody (GTX54076). Be the first to share your experience with this product.
