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IL3 Receptor alpha antibody [BR4MS]

Anti-IL3 Receptor alpha antibody [BR4MS] used in IHC (Paraffin sections) (IHC-P). GTX01890

Cat. No. GTX01890

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 BR4MS

Isotype

 IgG2b

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($609)
See all IL3 Receptor alpha products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

Prokaryotic recombinant protein corresponding to 101 amino acids of the external domain of the human CD123 molecule.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

interleukin 3 receptor subunit alpha , CD123 , IL3R , IL3RAY , IL3RX , IL3RY , hIL-3Ra

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012]

Database

Research Area

DATA IMAGES

Anti-IL3 Receptor alpha antibody [BR4MS] used in IHC (Paraffin sections) (IHC-P). GTX01890

GTX01890 IHC-P Image

IHC-P analysis of human high walled venule endothelium and plasmacytoid dendritic cells tissue using GTX01890 IL3 Receptor alpha antibody [BR4MS].

REFERENCE

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REVIEW

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Package List Price ($)
$ 609